Esto es sin duda una abducción de 0nce puntos, por lo menos...
Si la base del sustento diario del capitalismo, desde el crack del 29, era la sociedad de consumo.
Si la base neurofisiológica de la sociedad de consumo es el consumo impulsivo.
Si el consumo impulsivo se demuestra científicamente que es una adicción.
Entonces es hora de revisar seriamente lo que se considera adicción de lo que no.
Los llamados enteógenos, no generan adicción, pues por su carácter abductivo alimentan, desde tiempos "zoológicos" la inventiva y la creatividad.
Seguimos desnudando al emperador. Creo que ya solo le queda un piercing por ahí... "colgado en la punta". Tenía que estar bien colgado para colgarselo ahí, precisamente. Esto, ejem..., ¿quien se lo quita? Que a mí me da yuyu...!!!
Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
- Journal name:
- Nature Neuroscience
- Volume:
- 13,
- Pages:
- 635–641
- Year published:
- (2010)
- DOI:
- doi:10.1038/nn.2519
- Received
- Accepted
- Published online
Abstract
We found that development of obesity was coupled with emergence of a progressively worsening deficit in neural reward responses. Similar changes in reward homeostasis induced by cocaine or heroin are considered to be crucial in triggering the transition from casual to compulsive drug-taking. Accordingly, we detected compulsive-like feeding behavior in obese but not lean rats, measured as palatable food consumption that was resistant to disruption by an aversive conditioned stimulus. Striatal dopamine D2 receptors (D2Rs) were downregulated in obese rats, as has been reported in humans addicted to drugs. Moreover, lentivirus-mediated knockdown of striatal D2Rs rapidly accelerated the development of addiction-like reward deficits and the onset of compulsive-like food seeking in rats with extended access to palatable high-fat food. These data demonstrate that overconsumption of palatable food triggers addiction-like neuroadaptive responses in brain reward circuits and drives the development of compulsive eating. Common hedonic mechanisms may therefore underlie obesity and drug addiction.
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